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空姐出身的张嘉欣（杨思琦 饰）一生追求浪漫的爱情，无奈情路坎坷，突然宣布要和钻石王老五Gary（李铭顺 饰）结婚。同是空姐出身的三位好姐妹（张可颐、刘心悠、卫诗雅 饰）一同在马来西亚见证嘉欣大婚，嘉欣却临阵退缩，宁做落跑新娘一路出逃到杭州疗情伤。在情场中寻覓的没有脚的小飞鸟，最后被艺术折服，方停下脚步……一个商场中的女强人，以为抓紧老公不放会快乐，最后知痛，放手，才得到解脱的快乐。 一个极之重视外表的OL，三天之内180度转变，她真正需要的是有承担、能解决问题的男人，踏实的生活才会令她快乐。一个宅女，找到一个会令她笑的男人，就快乐了。三姐妹如何惩罚贱男为姐妹复仇？这出喜剧又将如何收场？出身警察世家的尹平安为人懒散，他的兄弟尹明扬是警界神枪手，夺“金枪”之誉，却不幸在一次追捕黑社会两大集团的混战中中枪惨死，明扬之友方正右手受伤致残，后其苦练左手，终回复当年枪法，并暗中追查杀害明扬之凶手。话虽如此……哎……汪滶摇头登船，明廷执意如此，若明廷来统苔湾，只怕……统不住的。少年全家惨遭灭门，苦练绝艺最后终有所成，大仇得报。Total quality management mainly includes the establishment of a quality assurance system: in terms of resources, attention should be paid to the quality assurance of raw materials and purchased parts, and suppliers should be carefully selected; In terms of design, the JIT management system requires the designed products to have strong flexibility. In terms of personnel, it emphasizes the quality of people's work and the sense of responsibility for product quality. In the process of processing, attention should be paid to quality process control. Only under the effect of total quality management can we ensure good quality in every link of JIT system, make it try its best to achieve "zero defects" and realize "zero inventory".尽管被调整到每周四晚9点播出，《妙女神探》平均每一集仍吸引到了710万观众。因此，TNT台已经续订了第四季，该季共有15集，将于2013年播出。